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N-Acetylcysteine (NAC) as antidote to gambling

June 17, 2026

Last updated: June 25, 2026


N-Acetylcysteine (NAC) might just be an antidote to the gambling crisis.

Multiple studies looking at its effect on gambling addiction, this one below showed NAC:

◆ Reduced pathological gambling scores (by nearly 50%)

◆ Reduced urges / thoughts of gambling

◆ Improved depression

◆ Reduced anxiety

◆ Reduced money lost due to gambling (by more than 50%)

This is due to its ability to lower extracellular glutamate in the nucleus accumbens in the brain - often elevated and drives compulsion in addiction.

Source: https://x.com/Outdoctrination/status/2038689717449892306?s=20