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Things that can lower or block serotonin

June 17, 2026

Last updated: June 20, 2026


Things that can lower or block serotonin: Aspirin - lowers plasma serotonin L-theanine - lowers brain serotonin Thiamine - lowers brain serotonin (in deficiency) Glycine - lowers brain serotonin Taurine - lowers brain serotonin Thyroid hormone T3 - lowers brain and nonbrain serotonin (in hypothyroidism) Ginger - lowers brain and non-brain serotonin, serotonin synthesis, and blocks serotonin Cyproheptadine - blocks serotonin Negative air ions - likely decrease brain and non-brain serotonin Vitamin E - lowers brain serotonin Magnesium - lowers brain serotonin (in deficiency) DHEA - blocks stress-induced serotonin synthesis (higher doses are estrogenic/bad) Avoiding seed oils - the linoleic acid increases blood serotonin Eating regularly - prevents excess linoleic acid in the blood Lysine - blocks serotonin 5-HT4 receptor (GI and mental function) Progesterone - inhibits serotonin synthesis Testosterone/DHT - inhibit serotonin synthesis

Source: https://x.com/lowmegatron/status/1890777476839641401